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Inflammation Enhances IL-2 Driven Differentiation of Cytolytic CD4 T Cells

Cytolytic CD4 T cells (CD4 CTL) have been identified in vivo in response to viral infections; however, the factors necessary for driving the cytolytic phenotype have not been fully elucidated. Our previously published work suggests IL-2 may be the master regulator of perforin-mediated cytotoxicity i...

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Detalles Bibliográficos
Autores principales: Workman, Aspen M., Jacobs, Ashley K., Vogel, Alexander J., Condon, Shirley, Brown, Deborah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930678/
https://www.ncbi.nlm.nih.gov/pubmed/24586481
http://dx.doi.org/10.1371/journal.pone.0089010