Small Molecule Inhibitors Target the Tissue Transglutaminase and Fibronectin Interaction

Tissue transglutaminase (TG2) mediates protein crosslinking through generation of ε−(γ-glutamyl) lysine isopeptide bonds and promotes cell adhesion through interaction with fibronectin (FN) and integrins. Cell adhesion to the peritoneal matrix regulated by TG2 facilitates ovarian cancer disseminatio...

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Detalles Bibliográficos
Autores principales: Yakubov, Bakhtiyor, Chen, Lan, Belkin, Alexey M., Zhang, Sheng, Chelladurai, Bhadrani, Zhang, Zhong-Yin, Matei, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930694/
https://www.ncbi.nlm.nih.gov/pubmed/24586660
http://dx.doi.org/10.1371/journal.pone.0089285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930694/
https://www.ncbi.nlm.nih.gov/pubmed/24586660
http://dx.doi.org/10.1371/journal.pone.0089285

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