Increasing Prion Propensity by Hydrophobic Insertion

Prion formation involves the conversion of proteins from a soluble form into an infectious amyloid form. Most yeast prion proteins contain glutamine/asparagine-rich regions that are responsible for prion aggregation. Prion formation by these domains is driven primarily by amino acid composition, not...

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Detalles Bibliográficos
Autores principales: Gonzalez Nelson, Aaron C., Paul, Kacy R., Petri, Michelina, Flores, Noe, Rogge, Ryan A., Cascarina, Sean M., Ross, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930707/
https://www.ncbi.nlm.nih.gov/pubmed/24586661
http://dx.doi.org/10.1371/journal.pone.0089286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930707/
https://www.ncbi.nlm.nih.gov/pubmed/24586661
http://dx.doi.org/10.1371/journal.pone.0089286

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