Cargando…

Optimization of a One-Step Heat-Inducible In Vivo Mini DNA Vector Production System

While safer than their viral counterparts, conventional circular covalently closed (CCC) plasmid DNA vectors offer a limited safety profile. They often result in the transfer of unwanted prokaryotic sequences, antibiotic resistance genes, and bacterial origins of replication that may lead to unwante...

Descripción completa

Detalles Bibliográficos
Autores principales: Nafissi, Nafiseh, Sum, Chi Hong, Wettig, Shawn, Slavcev, Roderick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930727/
https://www.ncbi.nlm.nih.gov/pubmed/24586704
http://dx.doi.org/10.1371/journal.pone.0089345