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Mitochondrial oxygen consumption deficits in skeletal muscle isolated from an Alzheimer’s disease-relevant murine model

BACKGROUND: Age is considered a primary risk factor for neurodegenerative diseases including Alzheimer’s disease (AD). It is also now well understood that mitochondrial function declines with age. Mitochondrial deficits have been previously assessed in brain from both human autopsy tissue and diseas...

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Detalles Bibliográficos
Autores principales: Schuh, Rosemary A, Jackson, Kathryn C, Schlappal, Anna E, Spangenburg, Espen E, Ward, Christopher W, Park, Ji H, Dugger, Natalie, Shi, Guo Li, Fishman, Paul S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930757/
https://www.ncbi.nlm.nih.gov/pubmed/24524276
http://dx.doi.org/10.1186/1471-2202-15-24