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Evidence of a vicious cycle in glutamine synthesis and breakdown in pathogenesis of hepatic encephalopathy–therapeutic perspectives
There is substantial clinical and experimental evidence that ammonia is a major factor in the pathogenesis of hepatic encephalopathy. In the article is demonstrated that in hepatocellular dysfunction, ammonia detoxification to glutamine (GLN) in skeletal muscle, brain, and likely the lungs, is activ...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930847/ https://www.ncbi.nlm.nih.gov/pubmed/23996300 http://dx.doi.org/10.1007/s11011-013-9428-9 |