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Synaptotagmin 7 functions as a Ca(2+)-sensor for synaptic vesicle replenishment

Synaptotagmin (syt) 7 is one of three syt isoforms found in all metazoans; it is ubiquitously expressed, yet its function in neurons remains obscure. Here, we resolved Ca(2+)-dependent and Ca(2+)-independent synaptic vesicle (SV) replenishment pathways, and found that syt 7 plays a selective and cri...

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Detalles Bibliográficos
Autores principales: Liu, Huisheng, Bai, Hua, Hui, Enfu, Yang, Lu, Evans, Chantell S, Wang, Zhao, Kwon, Sung E, Chapman, Edwin R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930910/
https://www.ncbi.nlm.nih.gov/pubmed/24569478
http://dx.doi.org/10.7554/eLife.01524