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Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression

The regulation of skeletal muscle mass depends on the balance between protein synthesis and degradation. The role of protein degradation and in particular, the ubiquitin proteasome system, and increased expression of the E3 ubiquitin ligases, MuRF1 and MAFbx/atrogin-1, in the regulation of muscle si...

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Detalles Bibliográficos
Autores principales: Baehr, Leslie M., Tunzi, Matthew, Bodine, Sue C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930915/
https://www.ncbi.nlm.nih.gov/pubmed/24600408
http://dx.doi.org/10.3389/fphys.2014.00069