Proteomic Analysis of Tendon Extracellular Matrix Reveals Disease Stage-specific Fragmentation and Differential Cleavage of COMP (Cartilage Oligomeric Matrix Protein)

During inflammatory processes the extracellular matrix (ECM) is extensively remodeled, and many of the constituent components are released as proteolytically cleaved fragments. These degradative processes are better documented for inflammatory joint diseases than tendinopathy even though the pathoge...

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Detalles Bibliográficos
Autores principales: Dakin, Stephanie Georgina, Smith, Roger Kenneth Whealands, Heinegård, Dick, Önnerfjord, Patrik, Khabut, Areej, Dudhia, Jayesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931053/
https://www.ncbi.nlm.nih.gov/pubmed/24398684
http://dx.doi.org/10.1074/jbc.M113.511972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931053/
https://www.ncbi.nlm.nih.gov/pubmed/24398684
http://dx.doi.org/10.1074/jbc.M113.511972

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