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Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells()
Spatial organisation of T cell receptor (TCR) and its coreceptor CD8 on the surface of live naïve and Ag-experienced CD8(+) T cells was resolved by fluorescence lifetime cross-correlation microscopy. We found that exposure of naïve CD8(+) T cells to antigen (Ag) causes formation of [TCR, CD8] functi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier/North-Holland Biomedical Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931270/ https://www.ncbi.nlm.nih.gov/pubmed/24263053 http://dx.doi.org/10.1016/j.imlet.2013.11.005 |