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CD133 facilitates epithelial-mesenchymal transition through interaction with the ERK pathway in pancreatic cancer metastasis

BACKGROUND: Pancreatic cancer is a lethal disease due to the high incidence of metastasis at the time of detection. CD133 expression in clinical pancreatic cancer correlates with poor prognosis and metastasis. However, the molecular mechanism of CD133-regulated metastasis remains unclear. In recent...

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Detalles Bibliográficos
Autores principales: Ding, Qiang, Miyazaki, Yumi, Tsukasa, Koichiro, Matsubara, Shyuichiro, Yoshimitsu, Makoto, Takao, Sonshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931313/
https://www.ncbi.nlm.nih.gov/pubmed/24468059
http://dx.doi.org/10.1186/1476-4598-13-15