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Osteocalcin Promotes β-Cell Proliferation During Development and Adulthood Through Gprc6a
Expanding β-cell mass through β-cell proliferation is considered a potential therapeutic approach to treat β-cell failure in diabetic patients. A necessary step toward achieving this goal is to identify signaling pathways that regulate β-cell proliferation in vivo. Here we show that osteocalcin, a b...
Autores principales: | Wei, Jianwen, Hanna, Timothy, Suda, Nina, Karsenty, Gerard, Ducy, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931403/ https://www.ncbi.nlm.nih.gov/pubmed/24009262 http://dx.doi.org/10.2337/db13-0887 |
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