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Anacardic acid, a histone acetyltransferase inhibitor, modulates LPS-induced IL-8 expression in a human alveolar epithelial cell line A549

Objective and design: The histone acetylation processes, which are believed to play a critical role in the regulation of many inflammatory genes, are reversible and regulated by histone acetyltransferases (HATs), which promote acetylation, and histone deacetylases (HDACs), which promote deacetylatio...

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Detalles Bibliográficos
Autores principales: Yasutake, Tetsuo, Wada, Hiroo, Higaki, Manabu, Nakamura, Masuo, Honda, Kojiro, Watanabe, Masato, Ishii, Haruyuki, Kamiya, Shigeru, Takizawa, Hajime, Goto, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931454/
https://www.ncbi.nlm.nih.gov/pubmed/24627774
http://dx.doi.org/10.12688/f1000research.2-78.v1