IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts

Activation of the innate immune system plays a key role in exacerbations of chronic lung disease, yet the potential role of lung fibroblasts in innate immunity and the identity of epithelial danger signals (alarmins) that may contribute to this process are unclear. The objective of the study was to...

Descripción completa

Detalles Bibliográficos
Autores principales: Suwara, M I, Green, N J, Borthwick, L A, Mann, J, Mayer-Barber, K D, Barron, L, Corris, P A, Farrow, S N, Wynn, T A, Fisher, A J, Mann, D A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931585/
https://www.ncbi.nlm.nih.gov/pubmed/24172847
http://dx.doi.org/10.1038/mi.2013.87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931585/
https://www.ncbi.nlm.nih.gov/pubmed/24172847
http://dx.doi.org/10.1038/mi.2013.87

Ejemplares similares