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IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts
Activation of the innate immune system plays a key role in exacerbations of chronic lung disease, yet the potential role of lung fibroblasts in innate immunity and the identity of epithelial danger signals (alarmins) that may contribute to this process are unclear. The objective of the study was to...
Autores principales: | Suwara, M I, Green, N J, Borthwick, L A, Mann, J, Mayer-Barber, K D, Barron, L, Corris, P A, Farrow, S N, Wynn, T A, Fisher, A J, Mann, D A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931585/ https://www.ncbi.nlm.nih.gov/pubmed/24172847 http://dx.doi.org/10.1038/mi.2013.87 |
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