Lovastatin Delays Infection and Increases Survival Rates in AG129 Mice Infected with Dengue Virus Serotype 2

BACKGROUND: It has been reported that treatment of DENV-infected cultures with Lovastatin (LOV), can affect viral assembly. The objective of this study was to evaluate the effect of LOV on the survival rate and viremia levels of DENV-2-infected AG129 mice. METHODOLOGY/PRINCIPAL FINDINGS: Mice were i...

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Detalles Bibliográficos
Autores principales: Martinez-Gutierrez, Marlen, Correa-Londoño, Luis A., Castellanos, Jaime E., Gallego-Gómez, Juan C., Osorio, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931612/
https://www.ncbi.nlm.nih.gov/pubmed/24586275
http://dx.doi.org/10.1371/journal.pone.0087412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931612/
https://www.ncbi.nlm.nih.gov/pubmed/24586275
http://dx.doi.org/10.1371/journal.pone.0087412

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