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Lovastatin Delays Infection and Increases Survival Rates in AG129 Mice Infected with Dengue Virus Serotype 2
BACKGROUND: It has been reported that treatment of DENV-infected cultures with Lovastatin (LOV), can affect viral assembly. The objective of this study was to evaluate the effect of LOV on the survival rate and viremia levels of DENV-2-infected AG129 mice. METHODOLOGY/PRINCIPAL FINDINGS: Mice were i...
Autores principales: | Martinez-Gutierrez, Marlen, Correa-Londoño, Luis A., Castellanos, Jaime E., Gallego-Gómez, Juan C., Osorio, Jorge E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931612/ https://www.ncbi.nlm.nih.gov/pubmed/24586275 http://dx.doi.org/10.1371/journal.pone.0087412 |
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