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Alterations of Mass Density and 3D Osteocyte Lacunar Properties in Bisphosphonate-Related Osteonecrotic Human Jaw Bone, a Synchrotron µCT Study

Osteonecrosis of the jaw, in association with bisphosphonates (BRONJ) used for treating osteoporosis or cancer, is a severe and most often irreversible side effect whose underlying pathophysiological mechanisms remain largely unknown. Osteocytes are involved in bone remodeling and mineralization whe...

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Detalles Bibliográficos
Autores principales: Hesse, Bernhard, Langer, Max, Varga, Peter, Pacureanu, Alexandra, Dong, Pei, Schrof, Susanne, Männicke, Nils, Suhonen, Heikki, Olivier, Cecile, Maurer, Peter, Kazakia, Galateia J., Raum, Kay, Peyrin, Francoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931622/
https://www.ncbi.nlm.nih.gov/pubmed/24586331
http://dx.doi.org/10.1371/journal.pone.0088481