Cargando…

Single-Cell Resolution Imaging of Retinal Ganglion Cell Apoptosis In Vivo Using a Cell-Penetrating Caspase-Activatable Peptide Probe

Peptide probes for imaging retinal ganglion cell (RGC) apoptosis consist of a cell-penetrating peptide targeting moiety and a fluorophore-quencher pair flanking an effector caspase consensus sequence. Using ex vivo fluorescence imaging, we previously validated the capacity of these probes to identif...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Xudong, Johnson, James R., Wilson, Bradley S., Gammon, Seth T., Piwnica-Worms, David, Barnett, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931650/
https://www.ncbi.nlm.nih.gov/pubmed/24586415
http://dx.doi.org/10.1371/journal.pone.0088855