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Single-Cell Resolution Imaging of Retinal Ganglion Cell Apoptosis In Vivo Using a Cell-Penetrating Caspase-Activatable Peptide Probe

Peptide probes for imaging retinal ganglion cell (RGC) apoptosis consist of a cell-penetrating peptide targeting moiety and a fluorophore-quencher pair flanking an effector caspase consensus sequence. Using ex vivo fluorescence imaging, we previously validated the capacity of these probes to identif...

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Detalles Bibliográficos
Autores principales:	Qiu, Xudong, Johnson, James R., Wilson, Bradley S., Gammon, Seth T., Piwnica-Worms, David, Barnett, Edward M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931650/ https://www.ncbi.nlm.nih.gov/pubmed/24586415 http://dx.doi.org/10.1371/journal.pone.0088855

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