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Exacerbation of Celecoxib-Induced Renal Injury by Concomitant Administration of Misoprostol in Rats
Nonsteroidal anti-inflammatory drugs (NSAIDs) can produce adverse effects by inhibiting prostaglandin (PG) synthesis. A PGE(1) analogue, misoprostol, is often utilized to alleviate NSAID-related gastrointestinal side effects. This study examined the effect of misoprostol on celecoxib renal toxicity....
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931696/ https://www.ncbi.nlm.nih.gov/pubmed/24586517 http://dx.doi.org/10.1371/journal.pone.0089087 |