Exacerbation of Celecoxib-Induced Renal Injury by Concomitant Administration of Misoprostol in Rats

Nonsteroidal anti-inflammatory drugs (NSAIDs) can produce adverse effects by inhibiting prostaglandin (PG) synthesis. A PGE(1) analogue, misoprostol, is often utilized to alleviate NSAID-related gastrointestinal side effects. This study examined the effect of misoprostol on celecoxib renal toxicity....

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Detalles Bibliográficos
Autores principales: Cooper, Dustin L., Murrell, Derek E., Conder, Christopher M., Palau, Victoria E., Campbell, Grace E., Lynch, Shaun P., Denham, James W., Hanley, Angela V., Bullins, Kenny W., Panus, Peter C., Singh, Krishna, Harirforoosh, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931696/
https://www.ncbi.nlm.nih.gov/pubmed/24586517
http://dx.doi.org/10.1371/journal.pone.0089087

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