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Transcription Factor Binding Sites Prediction Based on Modified Nucleosomes

In computational methods, position weight matrices (PWMs) are commonly applied for transcription factor binding site (TFBS) prediction. Although these matrices are more accurate than simple consensus sequences to predict actual binding sites, they usually produce a large number of false positive (FP...

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Detalles Bibliográficos
Autores principales: Talebzadeh, Mohammad, Zare-Mirakabad, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931712/
https://www.ncbi.nlm.nih.gov/pubmed/24586611
http://dx.doi.org/10.1371/journal.pone.0089226