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Genetic Association Analysis of ATP Binding Cassette Protein Family Reveals a Novel Association of ABCB1 Genetic Variants with Epilepsy Risk, but Not with Drug-Resistance

Epilepsy constitutes a heterogeneous group of disorders that is characterized by recurrent unprovoked seizures due to widely different etiologies. Multidrug resistance remains a major issue in clinical epileptology, where one third of patients with epilepsy continue to have seizures. Role of efflux...

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Detalles Bibliográficos
Autores principales: Balan, Shabeesh, Bharathan, Sumitha Prameela, Vellichiramal, Neetha Nanoth, Sathyan, Sanish, Joseph, Vijai, Radhakrishnan, Kurupath, Banerjee, Moinak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931716/
https://www.ncbi.nlm.nih.gov/pubmed/24586633
http://dx.doi.org/10.1371/journal.pone.0089253