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MCPerm: A Monte Carlo Permutation Method for Accurately Correcting the Multiple Testing in a Meta-Analysis of Genetic Association Studies

Traditional permutation (TradPerm) tests are usually considered the gold standard for multiple testing corrections. However, they can be difficult to complete for the meta-analyses of genetic association studies based on multiple single nucleotide polymorphism loci as they depend on individual-level...

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Detalles Bibliográficos
Autores principales: Jiang, Yongshuai, Zhang, Lanying, Kong, Fanwu, Zhang, Mingming, Lv, Hongchao, Liu, Guiyou, Liao, Mingzhi, Feng, Rennan, Li, Jin, Zhang, Ruijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931718/
https://www.ncbi.nlm.nih.gov/pubmed/24586601
http://dx.doi.org/10.1371/journal.pone.0089212