Inhibition of Post-Transcriptional RNA Processing by CDK Inhibitors and Its Implication in Anti-Viral Therapy

Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle and RNA polymerase II mediated transcription. Several pharmacological CDK inhibitors are currently in clinical trials as potential cancer therapeutics and some of them also exhibit antiviral effects. Olomoucine II and roscovitine,...

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Detalles Bibliográficos
Autores principales: Holcakova, Jitka, Muller, Petr, Tomasec, Peter, Hrstka, Roman, Nekulova, Marta, Krystof, Vladimir, Strnad, Miroslav, Wilkinson, Gavin W. G., Vojtesek, Borivoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931720/
https://www.ncbi.nlm.nih.gov/pubmed/24586613
http://dx.doi.org/10.1371/journal.pone.0089228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931720/
https://www.ncbi.nlm.nih.gov/pubmed/24586613
http://dx.doi.org/10.1371/journal.pone.0089228

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