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Conditional Deletion of Ferritin H in Mice Reduces B and T Lymphocyte Populations

The immune system and iron availability are intimately linked as appropriate iron supply is needed for cell proliferation, while excess iron, as observed in hemochromatosis, may reduce subsets of lymphocytes. We have tested the effects of a ferritin H gene deletion on lymphocytes. Mx-Cre mediated co...

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Detalles Bibliográficos
Autores principales: Vanoaica, Liviu, Richman, Larry, Jaworski, Maike, Darshan, Deepak, Luther, Sanjiv A., Kühn, Lukas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931725/
https://www.ncbi.nlm.nih.gov/pubmed/24586648
http://dx.doi.org/10.1371/journal.pone.0089270