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Tsc1-Tp53 loss induces mesothelioma in mice, and evidence for this mechanism in human mesothelioma

Mesothelioma is diagnosed in approximately 2,500 patients in the United States every year, most often arising in the pleural space, but also occurring as primary peritoneal mesothelioma. The vast majority of patients with mesothelioma die from their disease within 3 years. We developed a new mouse m...

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Detalles Bibliográficos
Autores principales: Guo, Yanan, Chirieac, Lucian R., Bueno, Raphael, Pass, Harvey, Wu, Wenhao, Malinowska, Izabela A., Kwiatkowski, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931745/
https://www.ncbi.nlm.nih.gov/pubmed/23851502
http://dx.doi.org/10.1038/onc.2013.280