Impairment of Drosophila Orthologs of the Human Orphan Protein C19orf12 Induces Bang Sensitivity and Neurodegeneration

Mutations in the orphan gene C19orf12 were identified as a genetic cause in a subgroup of patients with NBIA, a neurodegenerative disorder characterized by deposits of iron in the basal ganglia. C19orf12 was shown to be localized in mitochondria, however, nothing is known about its activity and no f...

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Detalles Bibliográficos
Autores principales: Iuso, Arcangela, Sibon, Ody C. M., Gorza, Matteo, Heim, Katharina, Organisti, Cristina, Meitinger, Thomas, Prokisch, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931782/
https://www.ncbi.nlm.nih.gov/pubmed/24586779
http://dx.doi.org/10.1371/journal.pone.0089439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931782/
https://www.ncbi.nlm.nih.gov/pubmed/24586779
http://dx.doi.org/10.1371/journal.pone.0089439

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