Serum and Glucocorticoid-Inducible Kinase1 Increases Plasma Membrane wt-CFTR in Human Airway Epithelial Cells by Inhibiting Its Endocytic Retrieval

BACKGROUND: Chloride (Cl) secretion by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) located in the apical membrane of respiratory epithelial cells plays a critical role in maintenance of the airway surface liquid and mucociliary clearance of pathogens. Previously, we and others hav...

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Detalles Bibliográficos
Autores principales: Bomberger, Jennifer M., Coutermarsh, Bonita A., Barnaby, Roxanna L., Sato, J. Denry, Chapline, M. Christine, Stanton, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931797/
https://www.ncbi.nlm.nih.gov/pubmed/24586903
http://dx.doi.org/10.1371/journal.pone.0089599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931797/
https://www.ncbi.nlm.nih.gov/pubmed/24586903
http://dx.doi.org/10.1371/journal.pone.0089599

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