Wat1/pop3, a Conserved WD Repeat Containing Protein Acts Synergistically with Checkpoint Kinase Chk1 to Maintain Genome Ploidy in Fission Yeast S. pombe

Aberrant chromosome segregation defects can lead to aneuploidy, a common characteristic of human solid tumors. Aneuploidy is generated due to defects in the mitotic spindle or due to inefficient mitotic checkpoint response. We have isolated a novel mutant allele of wat1, a WD repeat containing prote...

Descripción completa

Detalles Bibliográficos
Autores principales: Verma, Sumit Kumar, Ranjan, Rajeev, Kumar, Vikash, Siddiqi, Mohammad Imran, Ahmed, Shakil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931806/
https://www.ncbi.nlm.nih.gov/pubmed/24586893
http://dx.doi.org/10.1371/journal.pone.0089587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931806/
https://www.ncbi.nlm.nih.gov/pubmed/24586893
http://dx.doi.org/10.1371/journal.pone.0089587

Ejemplares similares