Role of the ERK Pathway for Oxidant-Induced Parthanatos in Human Lymphocytes

Reactive oxygen species (ROS) are formed by myeloid cells as a defense strategy against microorganisms. ROS however also trigger poly(ADP-ribose) polymerase 1- (PARP-1) dependent cell death (parthanatos) in adjacent lymphocytes, which has been forwarded as a mechanism of immune escape in several for...

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Detalles Bibliográficos
Autores principales: Akhiani, Ali A., Werlenius, Olle, Aurelius, Johan, Movitz, Charlotta, Martner, Anna, Hellstrand, Kristoffer, Thorén, Fredrik B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931820/
https://www.ncbi.nlm.nih.gov/pubmed/24586933
http://dx.doi.org/10.1371/journal.pone.0089646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931820/
https://www.ncbi.nlm.nih.gov/pubmed/24586933
http://dx.doi.org/10.1371/journal.pone.0089646

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