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Role of the ERK Pathway for Oxidant-Induced Parthanatos in Human Lymphocytes

Reactive oxygen species (ROS) are formed by myeloid cells as a defense strategy against microorganisms. ROS however also trigger poly(ADP-ribose) polymerase 1- (PARP-1) dependent cell death (parthanatos) in adjacent lymphocytes, which has been forwarded as a mechanism of immune escape in several for...

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Detalles Bibliográficos
Autores principales:	Akhiani, Ali A., Werlenius, Olle, Aurelius, Johan, Movitz, Charlotta, Martner, Anna, Hellstrand, Kristoffer, Thorén, Fredrik B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931820/ https://www.ncbi.nlm.nih.gov/pubmed/24586933 http://dx.doi.org/10.1371/journal.pone.0089646

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