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The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells
BACKGROUND: The standard treatment of ovarian cancer with chemotherapy often leads to drug resistance and relapse of the disease, and the need for development of novel therapy alternatives is obvious. The MOC31PE immunotoxin binds to the cell surface antigen EpCAM, which is expressed by the majority...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931919/ https://www.ncbi.nlm.nih.gov/pubmed/24528603 http://dx.doi.org/10.1186/1757-2215-7-23 |