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The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells

BACKGROUND: The standard treatment of ovarian cancer with chemotherapy often leads to drug resistance and relapse of the disease, and the need for development of novel therapy alternatives is obvious. The MOC31PE immunotoxin binds to the cell surface antigen EpCAM, which is expressed by the majority...

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Detalles Bibliográficos
Autores principales: Wiiger, Merete Thune, Bideli, Hemaseh, Fodstad, Øystein, Flatmark, Kjersti, Andersson, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931919/
https://www.ncbi.nlm.nih.gov/pubmed/24528603
http://dx.doi.org/10.1186/1757-2215-7-23