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Unique features of the transcriptional response to model aneuploidy in human cells

BACKGROUND: Aneuploidy, a karyotype deviating from multiples of a haploid chromosome set, affects the physiology of eukaryotes. In humans, aneuploidy is linked to pathological defects such as developmental abnormalities, mental retardation or cancer, but the underlying mechanisms remain elusive. The...

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Detalles Bibliográficos
Autores principales: Dürrbaum, Milena, Kuznetsova, Anastasia Yurievna, Passerini, Verena, Stingele, Silvia, Stoehr, Gabriele, Storchová, Zuzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932016/
https://www.ncbi.nlm.nih.gov/pubmed/24548329
http://dx.doi.org/10.1186/1471-2164-15-139