Misfolding of Mutated Vasopressin Causes ER-Retention and Activation of ER-Stress Markers in Neuro-2a Cells

Arginine-vasopressin (AVP) is a peptide hormone normally secreted from neuroendocrine cells via the regulated secretory pathway. In Familial Neurohypophyseal Diabetes Insipidus (FNDI), an autosomal dominant form of central diabetes insipidus, mutations of pro-vasopressin appear to accumulate in the...

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Detalles Bibliográficos
Autores principales: Yan, Zhongyu, Hoffmann, Andrea, Kaiser, Erin Kelly, Grunwald, William C., Cool, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932059/
https://www.ncbi.nlm.nih.gov/pubmed/24567768
http://dx.doi.org/10.2174/1876528901104010136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932059/
https://www.ncbi.nlm.nih.gov/pubmed/24567768
http://dx.doi.org/10.2174/1876528901104010136

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