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Human pluripotent stem cell models of autism spectrum disorder: emerging frontiers, opportunities, and challenges towards neuronal networks in a dish

Autism spectrum disorder (ASD) is characterized by deficits in language development and social cognition and the manifestation of repetitive and restrictive behaviors. Despite recent major advances, our understanding of the pathophysiological mechanisms leading to ASD is limited. Although most ASD c...

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Detalles Bibliográficos
Autores principales: Aigner, Stefan, Heckel, Tobias, Zhang, Jitao D., Andreae, Laura C., Jagasia, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932166/
https://www.ncbi.nlm.nih.gov/pubmed/24232378
http://dx.doi.org/10.1007/s00213-013-3332-1