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S100A8/A9 as a biomarker for synovial inflammation and joint damage in patients with rheumatoid arthritis
S100A8 and S100A9 are major leukocyte proteins, known as damage-associated molecular patterns, found at high concentrations in the synovial fluid of patients with rheumatoid arthritis (RA). A heterodimeric complex of S100A8/A9 is secreted by activated leukocytes and binds to Toll-like receptor 4, wh...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Internal Medicine
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932383/ https://www.ncbi.nlm.nih.gov/pubmed/24574827 http://dx.doi.org/10.3904/kjim.2014.29.1.12 |