Pancreatic Cancer Cells Isolated from Muc1-Null Tumors Favor the Generation of a Mature Less Suppressive MDSC Population

Mucin 1 (MUC1) is a transmembrane mucin glycoprotein that is over-expressed and aberrantly glycosylated in >80% of human pancreatic ductal adenocarcinoma (PDA) and is associated with poor prognosis. To understand the role of MUC1 in PDA, we have recently developed two mouse models of spontaneous...

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Detalles Bibliográficos
Autores principales: Kidiyoor, Amritha, Schettini, Jorge, Besmer, Dahlia Marie, Rego, Stephen Lee, Nath, Sritama, Curry, Jennifer Marie, Roy, Lopamudra Das, Dréau, Didier, Mukherjee, Pinku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932420/
https://www.ncbi.nlm.nih.gov/pubmed/24605110
http://dx.doi.org/10.3389/fimmu.2014.00067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932420/
https://www.ncbi.nlm.nih.gov/pubmed/24605110
http://dx.doi.org/10.3389/fimmu.2014.00067

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