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The paradox of NKp46(+) natural killer cells: drivers of severe hepatitis C virus-induced pathology but in-vivo resistance to interferon α treatment

OBJECTIVE: There is evidence that natural killer (NK) cells help control persistent viral infections including hepatitis C virus (HCV). The phenotype and function of blood and intrahepatic NK cells, in steady state and after interferon (IFN) α treatment has not been fully elucidated. DESIGN: We perf...

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Detalles Bibliográficos
Autores principales: Pembroke, Tom, Christian, Adam, Jones, Emma, Hills, Robert K, Wang, Eddie C Y, Gallimore, Awen M, Godkin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932740/
https://www.ncbi.nlm.nih.gov/pubmed/23665989
http://dx.doi.org/10.1136/gutjnl-2013-304472