IL-21 Promotes CD4 T Cell Responses by Phosphatidylinositol 3-Kinase–Dependent Upregulation of CD86 on B Cells

The cytokine IL-21 is a potent immune modulator with diverse mechanisms of action on multiple cell types. IL-21 is in clinical use to promote tumor rejection and is an emerging target for neutralization in the setting of autoimmunity. Despite its clinical potential, the biological actions of IL-21 a...

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Detalles Bibliográficos
Autores principales: Attridge, Kesley, Kenefeck, Rupert, Wardzinski, Lukasz, Qureshi, Omar S., Wang, Chun Jing, Manzotti, Claire, Okkenhaug, Klaus, Walker, Lucy S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2014
Materias:
Immune Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932810/
https://www.ncbi.nlm.nih.gov/pubmed/24470500
http://dx.doi.org/10.4049/jimmunol.1302082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932810/
https://www.ncbi.nlm.nih.gov/pubmed/24470500
http://dx.doi.org/10.4049/jimmunol.1302082

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