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Tumour T(1) changes in vivo are highly predictive of response to chemotherapy and reflect the number of viable tumour cells – a preclinical MR study in mice
BACKGROUND: Effective chemotherapy rapidly reduces the spin–lattice relaxation of water protons (T(1)) in solid tumours and this change (ΔT(1)) often precedes and strongly correlates with the eventual change in tumour volume (TVol). To understand the biological nature of ΔT(1), we have performed stu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932835/ https://www.ncbi.nlm.nih.gov/pubmed/24528602 http://dx.doi.org/10.1186/1471-2407-14-88 |