NOTCH signaling in immune-mediated bone marrow failure of aplastic anemia
Severe aplastic anemia is a rare bone marrow failure disease with the majority of cases caused by aberrant immune destruction of blood progenitors. Although the Th1-mediated pathology of aplastic anemia is well-described, the molecular mechanisms that drive disease progression remain ill-defined. Th...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932944/ https://www.ncbi.nlm.nih.gov/pubmed/25003012 http://dx.doi.org/10.4161/rdis.26764 |