NOTCH signaling in immune-mediated bone marrow failure of aplastic anemia

Severe aplastic anemia is a rare bone marrow failure disease with the majority of cases caused by aberrant immune destruction of blood progenitors. Although the Th1-mediated pathology of aplastic anemia is well-described, the molecular mechanisms that drive disease progression remain ill-defined. Th...

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Detalles Bibliográficos
Autor principal: Minter, Lisa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932944/
https://www.ncbi.nlm.nih.gov/pubmed/25003012
http://dx.doi.org/10.4161/rdis.26764