Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer’s disease

BACKGROUND: The progressive development of Alzheimer’s disease (AD) pathology follows a spatiotemporal pattern in the human brain. In a transgenic (Tg) mouse model of AD expressing amyloid precursor protein (APP) with the arctic (E693G) mutation, pathology spreads along anatomically connected struct...

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Detalles Bibliográficos
Autores principales: George, Sonia, Rönnbäck, Annica, Gouras, Gunnar K, Petit, Géraldine H, Grueninger, Fiona, Winblad, Bengt, Graff, Caroline, Brundin, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932948/
https://www.ncbi.nlm.nih.gov/pubmed/24517102
http://dx.doi.org/10.1186/2051-5960-2-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932948/
https://www.ncbi.nlm.nih.gov/pubmed/24517102
http://dx.doi.org/10.1186/2051-5960-2-17

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