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RNAi-mediated knockdown of FANCF suppresses cell proliferation, migration, invasion, and drug resistance potential of breast cancer cells

Fanconi anemia complementation group F protein (FANCF) is a key factor, which maintains the function of FA/BRCA, a DNA damage response pathway. However, the functional role of FANCF in breast cancer has not been elucidated. We performed a specific FANCF-shRNA knockdown of endogenous FANCF in vitro....

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Detalles Bibliográficos
Autores principales: Zhao, L., Li, N., Yu, J.K., Tang, H.T., Li, Y.L., He, M., Yu, Z.J., Bai, X.F., Zheng, Z.H., Wang, E.H., Wei, M.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932970/
https://www.ncbi.nlm.nih.gov/pubmed/24345874
http://dx.doi.org/10.1590/1414-431X20132938