Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation

OBJECTIVE: Colorectal cancer (CRC) is a major contributor to cancer mortality and morbidity. LIM kinase 2 (LIMK2) promotes tumour cell invasion and metastasis. The objectives of this study were to determine how LIMK2 expression is associated with CRC progression and patient outcome, and to use genet...

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Detalles Bibliográficos
Autores principales: Lourenço, Filipe C, Munro, June, Brown, Jennifer, Cordero, Julia, Stefanatos, Rhoda, Strathdee, Karen, Orange, Clare, Feller, Stephan M, Sansom, Owen J, Vidal, Marcos, Murray, Graeme I, Olson, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Colon
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932979/
https://www.ncbi.nlm.nih.gov/pubmed/23585469
http://dx.doi.org/10.1136/gutjnl-2012-303883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932979/
https://www.ncbi.nlm.nih.gov/pubmed/23585469
http://dx.doi.org/10.1136/gutjnl-2012-303883

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