A case of minor BCR-ABL1 positive acute lymphoblastic leukemia following essential thrombocythemia and originating from a clone distinct from that harboring the JAK2-V617F mutation

Here we report on a case of Philadelphia chromosome positive B lymphoblastic leukemia (Ph(+)ALL), which developed following a long duration of essential thrombocythemia (ET). A mutational analysis of Janus Kinase 2 (JAK2) revealed that the V617F mutation was present in granulocytes and in hematopoie...

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Detalles Bibliográficos
Autores principales: Nagai, Yuya, Kawahara, Masahiro, Sugino, Noriko, Shimazu, Yayoi, Hishizawa, Masakatsu, Yamashita, Kouhei, Kadowaki, Norimitsu, Takaori-Kondo, Akifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932988/
https://www.ncbi.nlm.nih.gov/pubmed/24528501
http://dx.doi.org/10.1186/2162-3619-3-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932988/
https://www.ncbi.nlm.nih.gov/pubmed/24528501
http://dx.doi.org/10.1186/2162-3619-3-6

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