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A case of minor BCR-ABL1 positive acute lymphoblastic leukemia following essential thrombocythemia and originating from a clone distinct from that harboring the JAK2-V617F mutation
Here we report on a case of Philadelphia chromosome positive B lymphoblastic leukemia (Ph(+)ALL), which developed following a long duration of essential thrombocythemia (ET). A mutational analysis of Janus Kinase 2 (JAK2) revealed that the V617F mutation was present in granulocytes and in hematopoie...
Autores principales: | Nagai, Yuya, Kawahara, Masahiro, Sugino, Noriko, Shimazu, Yayoi, Hishizawa, Masakatsu, Yamashita, Kouhei, Kadowaki, Norimitsu, Takaori-Kondo, Akifumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932988/ https://www.ncbi.nlm.nih.gov/pubmed/24528501 http://dx.doi.org/10.1186/2162-3619-3-6 |
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