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Human Lung Mast Cell Products Regulate Airway Smooth Muscle CXCL10 Levels

In asthma, the airway smooth muscle (ASM) produces CXCL10 which may attract CXCR3(+) mast/T cells to it. Our aim was to investigate the effects of mast cell products on ASM cell CXCL10 production. ASM cells from people with and without asthma were stimulated with IL-1β, TNF-α, and/or IFNγ and treate...

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Detalles Bibliográficos
Autores principales: Alkhouri, H., Cha, V., Tong, K., Moir, L. M., Armour, C. L., Hughes, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933026/
https://www.ncbi.nlm.nih.gov/pubmed/24648846
http://dx.doi.org/10.1155/2014/875105