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Sectorial loss of retinal ganglion cells in inherited photoreceptor degeneration is due to RGC death

AIMS: To investigate the cause of retinal ganglion cell (RGC) loss in dystrophic aged Royal College of Surgeons (RCS) rats. METHODS: RCS-p+ (dystrophic) female rats of postnatal times (P365, P450 and P540) and age-matched RCS-p1 rdy+ (non-dystrophic) rats were used. In whole-mounted retinas, RGCs we...

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Detalles Bibliográficos
Autores principales: García-Ayuso, Diego, Salinas-Navarro, Manuel, Nadal-Nicolás, Francisco Manuel, Ortín-Martínez, Arturo, Agudo-Barriuso, Marta, Vidal-Sanz, Manuel, Villegas-Pérez, María P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933073/
https://www.ncbi.nlm.nih.gov/pubmed/24326325
http://dx.doi.org/10.1136/bjophthalmol-2013-303958